Join NursingCenter to get uninterrupted access to this Article. Spironolactone is a potassium-sparing diuretic and selective aldosterone blocker used off-label in dermatology for treatment of acne and hirsutism in women. It was first investigated as a treatment for acne because of its antiandrogen properties in a study published in the British Journal of Dermatology in Goodfellow et al. Androgen hormones are produced in the adrenal glands and the gonads, but more potent forms of androgen are produced in the peripheral tissues from steroid precursors. When used for the treatment of acne and hirsutism, the mechanism of action of spironolactone is not completely understood.
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Oral Spironolactone in Post-teenage Female Patients with Acne Vulgaris
Spironolactone Acne - 11 Things a Dermatologist Wants You To Know
There is limited evidence on the safety and efficacy of spironolactone in the treatment of women with acne. Thus, for many dermatologists spironolactone remains an alternative rather than a mainstay treatment for female patients with acne. An electronic medical records search tool was used to select data from a group of women who received spironolactone to treat acne and were evaluated with the comprehensive acne severity scale CASS before treatment and at all follow-up visits. Data points were collected for CASS scores at each follow-up visit, concurrent and previous treatments, and side effects. These data points were used to draw conclusions about the safety and efficacy of spironolactone in this patient population. There were patients that met all eligibility requirements.
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Spironolactone: 11 things a dermatologist wants you to know about the acne treatment
Cutis September focus on atopic dermatitis issue now available. Correspondence: Adam J. For these patients, antihormonal therapy such as spironolactone is a valid and efficacious option.
If you haven't heard of spironolactone, it's a prescription drug used to treat health issues like high blood pressure and heart failure. However, what most people don't know is that it can be used as an acne treatment , too. Alice Lang , a year-old blogger from North Wales, discovered this after nearly 10 years of struggling with acne and experimenting with a wide range of prescribed medications, including birth control. Lang recently opened up to Popsugar about her experience, and how spironolactone ultimately saved her skin. It was while she was working in Vietnam — Lang is an avid traveler — that her blemishes became more severe than ever, and she realized it was time to explore other options.