Scalp follicle penetration

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Skip to search form Skip to main content. Transfollicular drug delivery: penetration of drugs through human scalp skin and comparison of penetration between scalp and abdominal skins in vitro. The penetration pathway for drugs through the scalp skin was examined using fluorescent probes. View on PubMed.
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Transfollicular drug delivery: current perspectives

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[Full text] Transfollicular drug delivery: current perspectives | RRTD

Javascript is currently disabled in your browser. Several features of this site will not function whilst javascript is disabled. Received 12 July Published 20 April Volume Pages 1—
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Follicular penetration of topically applied caffeine via a shampoo formulation.

In order to quantitatively investigate the importance of transfollicular pathway for drug delivery, drug penetration through human scalp skin was investigated using liquid formulations containing lipophilic and hydrophilic drugs in vitro. The penetration pathway for drugs through the scalp skin was examined using fluorescent probes. Additionally, the drug penetration through the scalp skin was compared with that via human abdominal skin to clarify the usefulness of intrafollicular delivery. Lipophilic melatonin MT and ketoprofen KP showed high permeabilities through the scalp skin, although the flux of KP was much higher.
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