Adult onset multiple sclerosis

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Monday, July 15, 2019
At one time, it was thought that MS rarely developed in people over 50 but opinion is changing as more cases are now being identified. This study looked at the characteristics of MS when it begins over the age of People in south-east Wales whose MS began at age 50 or above were identified from a regional database of people with MS. Some distinct differences were found compared with those whose MS began at a younger age. The researchers found that sensory and motor symptoms were more frequently found, there were fewer relapses and faster progression of disability.
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Late-Onset Multiple Sclerosis Doubled in Women Over Last 60 Years

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Multiple sclerosis - Symptoms and causes - Mayo Clinic

The introduction of new diagnostic criteria and lifestyle changes over the decades, including fewer childbirths and a higher occurrence of obesity, may indicate an epidemiological change contributing to an increase in late-onset multiple sclerosis in women. This study analyzed whether exposure to risk factors happened early in life or closer to onset, trends in incidence according to the presenting symptoms at onset optic, brainstem, or sensory , and whether perinatal circumstances or seasonality of birth are considered risk factors. The study population included 19, patients 12, women and men. The increase in incidence, however, was not consistent across age groups or clinical subgroups. The age-at-onset analysis determined that, although all age groups and sexes experienced a positive local drift, women aged had the highest relative increase in incidence between the decades. The study suggests that a reason for an increase in incidence is the introduction of new diagnostic criteria and tools, including magnetic resonance imaging.
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Late-Onset Multiple Sclerosis

When it comes to age, multiple sclerosis MS doesn't discriminate. This is called late-onset MS and it's commonly defined as the occurrence of the first MS symptoms after age The way the disease manifests in late-onset MS can be different from what normally happens in adult-onset MS, which most commonly affects people in their mids and 30s.
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In multiple sclerosis, the protective coating on nerve fibers myelin is damaged and may eventually be destroyed. Depending on where the nerve damage occurs, MS can affect vision, sensation, coordination, movement, and bladder and bowel control. Multiple sclerosis MS is a potentially disabling disease of the brain and spinal cord central nervous system. In MS , the immune system attacks the protective sheath myelin that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause permanent damage or deterioration of the nerves.
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(2)

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