Alternative treatment for chronic anal fissure

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Tuesday, May 7, 2019
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Between October and January , 10 patients diagnosed with chronic anal fissure at the Pelvic Floor Centre - University Hospital of Malmo, Sweden were treated with percutaneous tibial nerve stimulation. Pre-treatment evaluation included detailed medical history and anorectal examination. Patients were included in the study if they were older than 18 years and had symptoms of chronic anal fissure for at least 6 months.
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Chronic anal fissure: botulinum toxin type A injection

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New Protocol to Treat Anal Fissures | Columbia University Department of Surgery

Diltiazem hydrochloride is a calcium channel blocker and potent vasodilator. It increases blood flow to smooth muscles and relaxes muscle tone. Anal fissure is a common and painful problem that involves a tear or ulcer in the squamous epithelium of the anus, usually located in the posterior midline. The most common cause of anal fissure is passing particularly hard stools, leading to trauma. Other causes include inflammatory bowel disease, childbirth and sexually transmitted infection [ 8 ]. Although the aetiology of chronic anal fissure is uncertain, it is assumed that pain causes an increased sphincter pressure leading to ischaemia of the anal sphincter. This inhibits fissure healing, generating a vicious circle of pain, constipation and prolonging of the healing process [ 7 ].
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Chronic anal fissure: 2% topical diltiazem hydrochloride

Language: English French. Surgical sphincterotomy for chronic anal fissure can cause fecal incontinence. This has led to the investigation of nonsurgical treatment options that avoid permanent damage to the internal anal sphincter. We conducted a retrospective, ongoing chart review with telephone follow-up of 88 patients treated for chronic anal fissure between November and December During the first half of the study period, patients were treated with topical nitroglycerin and pneumatic dilatation.
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Most cases of chronic fissure do not respond to medical treatment. Razi and Ibn Sina were 2 of the best-known scientists of ancient Persia. The purpose of this study was to find out new scientific evidence in modern medicine about their recommendations, in order to find certain clues to conduct useful researches in the future.
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